About
Mystelle Ruble, PMP, is a Senior Strategy and Operations Executive with over 19 years of leadership experience managing large-scale, high-impact programs for federal government clients, specifically within the international development and social impact sectors. As a "professional problem-solver" and certified Project Management Professional (PMP), she has a proven track record of driving strategic growth, operational excellence, and organizational transformation in complex, multi-stakeholder environments.
Throughout her career, Mystelle has managed strategic portfolios valued at over $120 million, delivering quantifiable results in peacebuilding, economic growth, civic engagement, and social resilience. Her leadership has contributed to the creation of 35,000 jobs and the support of over 5,000 SMEs globally. She is a distinguished leader in crisis management, having navigated projects through military coups and active conflicts while maintaining 100% staff safety and program continuity.
Core Capabilities:
Mystelle has led proposal development efforts resulting in a $5 billion umbrella contract win and has spearheaded USAID proposals valued up to $200 million. Her deep knowledge of federal acquisition lifecycles (FAR/ADS) and compliance protocols makes her an asset for organizations seeking to navigate the U.S. government contracting landscape.She is a seasoned resource for insights on fragile and conflict-affected environments in the Middle East, Asia, West Africa, and Latin America. Her experience includes presenting at industry forums like USAID’s TechCon and authoring winning entries for Digital Development awards. Mystelle has mentored multidisciplinary and remote teams of up to 80+ global staff, facilitating leadership development and cultural inclusivity across diverse geographies.
Education and Background:
Mystelle holds a Master of Science in Conflict Analysis and Resolution from George Mason University’s Carter School and a Bachelor of Science in Foreign Service with a concentration in Middle East Studies from Georgetown University. Mystelle currently serves on the Board of Directors for Grace Episcopal Church, where she provides financial oversight, and on the George Mason University Carter School Alumni Board as Secretary. She possesses professional working proficiency in French and basic comprehension of Spanish and Arabic. Based in Washington, D.C., she is qualified for Public Trust/Secret clearance.